| Multifactorial pathogenic mechanisms take part in cardiovascular changes in chronic liver disease and them Include
neurohumoral and vascular dysregulations. Evidences advocate that cirrhotic liver sickness associated cardiovascular
abnormalities result in the pathogenesis of severa fatal complications which includes ascites, hepatorenal syndrome,
hepatopulmonary syndrome, gastro esophageal varices and spontaneous bacterial peritonitis. The reasons for persistent
hepatitis are numerous. It can be infective as in viral like Hepatitis B, Hepatitis C, Hepatitis D, additionally other viruses like
Cytomegalovirus, Epstein Barr virus. Autoimmune situations like Primary biliary cirrhosis and primary sclerosing
cholangitis. Other causes are non-alcoholic fatty liver disorder, alcoholic liver ailment and drug caused hepatitis,
Cryptogenic & metabolic or hereditary disorders like Wilson’s ailment, Haemochromatosis, alpha-1 antitrypsin deficiency
also make a contribution to liver cirrhosis.The most commonplace reasons for cirrhosis of these are persistent hepatitis C,
alcohol associated liver disorder, non-alcoholic fatty liver disorder (NAFLD), non-alcoholic steatohepatitis (NASH) and
chronic hepatitis B. Primary Biliary associated cirrhotic liver is rare as compared to the othersddd |
