COMPARISON OF INTRA ARTICULAR LOW DOSE SUFENTANIL, ROPIVACAINE, AND COMBINED SUFENTANIL AND ROPIVACAINE ON POST-OPERATIVE ANALGESIA OF KNEE SURGERY |
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| Language |
ENGLISH |
| Corres.Author |
Dr. Balaganesh S |
| Email |
jaipharma2007@gmail.com |
| Accepted Date |
20017-12-15 21:19:07 |
| File size |
|
| No of Downloads |
336 |
| Published by |
www.ijcpcr.com |
| Full Text |
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| The impact of intra-articular injection of local anaesthetic (ropivacaine), opioid (sufentanil) and the combination of these two (ropivacaine combined with sufentanil) after single-bundle anterior cruciate ligament repair has been compared to the effect of combination local anaesthetic and opioid in post-operative analgesia. In a prospective randomized double-blind design, 120 patients undergoing isolated anterior cruciate ligament reconstruction under epidural analgesia were assigned randomly to 4 groups; group A (n = 30) received 30 mL of 0.9% saline as control group; group B (n = 30) received 10 mg of ropivacaine and 2 lg of sufentanil as control group. Group C (n = 30) obtained 10 mg of 0.9 percent saline in 30 mL. At the end of the procedure, ropivacaine obtained 2 lg sufentanil in 30 mL 0.9 percent saline, group D (n = 20) in 30 mL 0.9 percent saline. Pain was measured with the use of a 100-mmm. Visual Analog Scale (VAS) tested at 6 and 24 h post-surgery. In successful straight leg raising exercise, the pain VAS ratings, the quality of sleep and the status of supplementary analgesia drugs administered during the first 24 h were also gathered. Each of the three experiment groups had significantly lower pain scores than the control group in each aspect. Group B (sufentanil ropivacaine) had a substantially lower pain score relative to group C (ropivacaine) and group D (sufentanil) at 6 and 24 h after surgery. Sleep characteristics were substantially better in patients in group B, C or D than in group A. Significantly more group A patients received supplemental analgesia relative to group B, C or D. In group B, no patient needed supplementary analgesia to obtain intramuscular dolantin. Intra-articular opioid (sufenta-nil) injection, local anaesthetic (ropivacaine) injection, or a combination of these two types of agents can significantly reduce pain after anterior cruciate ligament reconstruction. In conjunction with intra-articular opioid injection and local anaesthetic therapy, the analgesic effect was stronger than that of sufentanil or ropivacaine alone.ddd |
