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THE AUTOIMMUNITY’S FOOTPRINT IN PEDIATRICS: TYPE 1 DIABETES MELLITUS
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Pediatric autoimmune illnesses are uncommon, and when they do arise, they can be difficult to diagnose and treat. Many c hildren systemic autoimmune illnesses are distinct from those that affect adults, leading to confusion. A particular issue fo r doctors and researchers caring for youngsters who have been harmed by these maladies. When the body's own immune system malfuncti ons, autoimmune illnesses develop. The immune system targets and destroys healthy cells or piece of tissue There are over 80 different forms of autoimmune disorders. Specialist publications have cited them, but the exact cause of autoimmune diseases is yet unknown or unidentified. They could happen more frequently. Among people who are genetically predisposed to autoimmune conditions. An autoimmune disease is a condition in which the body's immune may harm one or more types of organs or tissues, implying th at a person/health patient's may be jeopardized. At the age of one year and three months, patient S. A. M. was diagnosed with type 1 diabetes mellitus. Diabetic ketoacidosis (pH 7.82; bicarbonate 6 mmol/L; base excess (BE) 21.0 mmol/L), glycemia 552 mg/dL, glycosuria, ketonuria, and HbA1c 12.0 percent were all present at the time of commencement. The patient's progress over the next eight years was positive, with an average HbA1c of 8% throughout that time. At the age of nine, the patient's yearly examinati on reveals Ig A type Ac anti transglutaminase 155 U/mL (normal values 0 10 U/mL) and Ig A anti gliadin antibody 30 U/mL (normal values 0 21 U/mL), prompting a duodenal biopsy. The histological findings revealed Marsh III celiac disease. As an autoimmune di sease, type 1 diabetes is linked to other autoimmune disorders. Regular screening (annually) beginning the first year after diabetes development is required for early detection of related autoimmune disorders in the absence of clinical symptoms. All family members must be examined if there is a familial aggregation of autoimmune disorders. The management of type 1 diabetes and its complications in the short and long term is dependent on early detection and treatment of the autoimmune disorders that accompan y itddd