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A RANDOMISED LONGITUDINAL TRIAL COMPARED THE EFFECTS OF EARLY CHOLECYSTECTOMY VERSUS DELAYED CHOLECYSTECTOMY IN PATIENTS WITH MILD TO SEVERE ACUTE BILIARY PANCREATITIS
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In developing countries, gallstone disease is the most common cause of acute pancreatitis, accounting for up to 75% of cases. Biliary calculi were the aetiology in nearly half of the patients (25.1 percent) admitted for acute pancreatitis in Malaysia, according to a retrospective study conducted over several years (10.7 percent). Patients who have had biliary pancreatitis may have repeated episodes of biliary pancreatitis, CBD obstruction, cholangitis, or biliary colics. To avoid repeated biliary events, cholecystectomy and biliary tree stone removal remain the mainstay of care. We are aimed to achieve the effectiveness of Cholecystectomy in Early Vs Delayed treatment in patients with Severe to Mild Acute Biliary Pancreatitis compared through a Randomized Longitudinal Trail. Due to a clear assumption of CBD stones based on laboratory biochemical parameters and imaging results, 15 patients (50 percent) in the early group and 15 patients (50 percent) in the delayed group underwent an ERCP prior to cholecystectomy. ES and stone extraction were performed on 30 of the 24 patients. ERCP revealed no signs of a CBD stone in the remaining patient. In terms of patients undergoing pre cholecystectomy ERCP, there is no substantial difference between the two classes. As compared to delayed laparoscopic cholecystectomy, the results of this study of patients with mild to moderate ABP show that laparoscopic cholecystectomy with IOC performed within the same index admission reduces recurrent biliary events and reduces overall duration of hospital stay. Furthermore, there is no difference in the need for open surgery conversion, surgery length, or complication rate between early and delayed cholecystectomy. As a result, we suggest early laparoscopic cholecystectomy in patients with mild to moderate ABP, and we hope that as more evidence and research become available, early laparoscopic cholecystectomy will become the standard of care in the treatment of mild to moderate ABP in the near future.ddd