THE RELATIONSHIP BETWEEN SERUM LACTATE LEVELS AND THE OCCURRENCE OF CONTRAST-INDUCED ACUTE KIDNEY INJURY AND PATIENTS' LONG-TERM PROGNOSIS, IN THE MIDST OF AN EMERGENCY CORONARY ARTERY PERCUTANEOUS INTERVENTION |
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| Language |
English |
| Corres.Author |
Dr. S. Selvakumar |
| Email |
Selvakumar@gmail.com |
| Accepted Date |
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| File size |
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| No of Downloads |
245 |
| Published by |
IJCPCR |
| Full Text |
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| The third leading cause of hospital-acquired acute renal failure is iatrogenic renal impairment caused by contrast media. Contrast-induced acute kidney injury (CI-AKI) is linked to hospital mortality, as well as one- and two-year mortality. An increase in lactate indicators over time indicates negative clinical outcomes. Lactate is a good microcirculation biomarker because it is closely related to capillary perfusion. This was a prospective and registration research project. From March 2016 to March 2017, 250 AMI participants who underwent emergency PCI at Hospital were chosen. The occurrence of CI-AKI was determined by univariate analysis. The accuracy and best cut-off values of lactate for predicting CI-AKI were determined using the receiver operating characteristic (ROC) curve and the corresponding area under curve (AUC). The survival analysis was performed using the Kaplan–Meier method, and the log rank test was used to compare the two groups. Using multivariate Cox regression analysis combined with the backward stepwise method, the predictors of clinical outcomes in AMI patients during a 1-year follow-up after PCI were investigated. Preoperative high lactate levels may be an independent risk factor in patients who develop CI-AKI and an important predictor of long-term poor cardiorenal outcomes with AMI undergoing emergency PCI, according to the findings of this study. More large samples and prospective randomized controlled trials in other institutional settings are needed to confirm this findingddd |
