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STUDY OF ROLE OF PROPHYLACTIC ANTIBIOTICS USE IN PATIENTS WITH ACUTE PANCREATITIS IN SOUTH INDIANS
Article Information
Language English
Corres.Author Dr.Kalyan Seetharamaiah V
Email drvrvkk@gmail.com
Accepted Date
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Published by IJCPCR
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Prophylactic antibiotics are used frequently for acute pancreatitis (AP). Consensus guidelines do not recommend this currently, based on moderate quality evidence. The development of pancreatic infection is associated with the development of a deteriorating disease with subsequent high morbidity and mortality. The average length of stay was 13 days and 12 days in groups A and B respectively. MODS developed in 10 of 30 pts in grp A, whereas in 12 of 30 pts in grp B.IPN was diagnosed in 4 pts in grp A and 2 patient in grp B. 8 patients in grp A and 10 patients in grp B suffered mortality. The use of prophylactic antibiotics does not add to the benefit in the outcome of patients with acute pancreatitis unless infection of necrosis has developed when therapeutic antibiotics are given. Instead, antibiotic may add to the organ failure that is frequently present in these patientsddd