| In today's pharmaceutical industry, optimization has arisen as a technique for finding the best compromise response to a
specific problem. The term optimization refers to the process of improving something or making it work better. Finding a
perfect, effective, or functional solution is what optimization is all about. The present review article aims at determining the
various possible techniques available to enhance the quality, safety and efficacy of pharmaceutical formulations by
exploring most suitable and practically applicable experimental designs (ED) and optimization techniques The screening
methods discussed here include factorial design, fractional factorial designs, full factorial design, mixture designs etc.
Experimental designs and optimization techniques are the tools that are simultaneously and systematically used to identify
various types of problems that may influence research, development and production of pharmaceutical formulationsddd |
