| Because most studies have focused on adult populations, little is known regarding the consequences of AN in children and
adolescents. Renal problems affect about 70% of AN patients at some point in their life, with a 5.2 percent chance of
developing significant kidney disease, including deadly renal failure, after 21 years of AN. Fichter et almortality .'s
research has recently yielded some interesting results. The goal of this study was to assess the renal function of hospitalised
AN patient by measuring creatinine levels in the blood and determining the glomerular filtration rate using several
formulae (GFR). In this study, the connection between GFR and intrinsic patient variables was also investigated. Cockroft–
Gault, Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI),
MAYO Clinic Quadratic equation (MCQ), and Schwartz formulae were used to calculate it (Annex 1). Unless otherwise
noted, the GFR test results were adjusted to the body surface area (standard = 1.73 m2) in order to draw comparisons. The
mean plus standard deviation (mean + SD) was used to report continuous variables. 45 percent of the 51 patients had a
GFR of less than 90 mL/min/1.73 m2 using the Cockroft–Gault formula, compared to 28 percent using the MDRD method,
14 percent using the CKD-EPI formula, 12 percent using the MCQ formula, and 4% using the Schwartz formula. Renal
issues in adolescent anorexic patients are given little attention in this therapeutic setting, leading in poor results. More
study is needed to understand the link between GFR and refeeding, as well as the long-term effects of severe starvation on
the kidneyddd |
