In few studies earlier showed upon determining fructosamine reflecting the concentration of blood glucose over the period
of 2-3 weeks whereas HbA1c showed concentrations of blood glucose level for last 6-8 weeks. Whereas the amount of
fructosamine increased in diabetes thought to constitute to the long term complications of the disease. The fructosamine
assay is affected by decreased serum albumin concentrations in conditions like nephrotic syndrome and hepatic disease. A
combination of fructosamine and HbA1c determination is useful in type2-DM. 25 cases of controls and 25 patients were
analysed for lipid profile, FBS and PLBS, HbA1c, fructosamine and MAU with diasys kits for assays. Mean value of
HbA1c in controls and patients with type-2DM was 4.72 and 9.32 and mean value of fructosamine was 200.7 and 378.9
respectively. The p value for HbA1c and fructosamine in controls and patients of diabetes showed highly significant (p
value < 0.0001) when taken as controls of HbA1c to the controls of serum fructosamine and patients of type-2 DM with
HbA1c to patients of DM with fructosamine. The highly significant of levels of HbA1c to fructosamine shows that in
patients of type2-DM fructosamine is an important test in combination to HbA1c estimationddd |