| The skin, the body's largest organ and its primary interface with the outside world, makes up over 10% of the entire body.
Butenafine is a popular antifungal agent for treating fungal infections on the skin. It is available as creams, gels, solutions,
and sprays. Among other uses, Butenafine is an ally amine antifungal agent commonly used to treat dermatophyte
infections. Aspergillus, Cryptococcus, and some species of Candida are also reported to have good activity against it in
vitro. As a result of the inhibition of squalene epoxidase in the biosynthesis of fungal ergosterol, butenafine induces the
accumulation of intracellular squalene and death of cells. Film-forming polymers may be used to form a matrix in either
liquids or semisolids. There is sufficient substance in the formed film to ensure sustained release of the drugddd |
