| The most significant parasite in terms of economic impact in the production of small ruminants is Haemonchus contortus,
the cause of haemonchosis. Chemotherapy control has failed since drug-resistant strains have quickly emerged. Alternative
leads, particularly those from plants, are continuously sought after. C.succulenta aerial portions and S. molle bark were
evaluated for their anti-helmintic properties against H.contortus. A motility test for adults and an egg hatching inhibitory
test were used to assess in vitro adulticidal and egg hatching inhibitory effects of the extracts. The adulticidal activity of the
extracts at higher doses (10 and 5 mg/ml) was substantially greater than that of albendazole and significantly superior to the
negative control (p<0.05). Similarly, S. molle and C. succulenta extracts had relative egg hatch suppression efficacy values
of 96% and 88%, respectively, within 48 hours of treatment at 1 mg/ml. A crude methanolic extract of the plants was found
to be effective in inhibiting egg hatching and adulticidal effects in H. contortusddd |
