| After endoscopic sinus surgery, patients with chronic rhinosinusitis with polyps (CRSwP) should get long-term treatment
with low-dose clarithromycin to test its effectiveness and safety (ESS). We found 10 people who had CRSwP and had them
undergo bilateral electroshock therapy (ESS). After surgery, patients were given nasal saline solution and steroid sprays to
cleanse out their nasal passages (beclomethasone). During follow-up, when nasal obstruction, odour loss, headache, and the
onset of viscous secretions appeared in some patients, their symptoms worsened. As a result, all patients continued treatment
with saline nasal irrigation, topical steroid therapy, and macrolide (clarithromycin 500 mg/pill: 1 pill per day for 3 days per
week). It was determined that the effectiveness of therapy was determined by conducting a SNOT-22 questionnaire and an
endoscopic appearance score (EAS). Sneezing, As well as, hyposmia, thick mucus secretions on the SNOT-22, and reduced
secretions and enlargement of the nasal mucosa on the EAS all exhibited statistically significant improvements (p<0.05) in
both tests, according to the researchers' findings. This study's early findings suggest an antibacterial and immunomodulatory
effect of low-dose clarithromycin for a duration of one month on CRSwP patient complaintsddd |
