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A STUDY IN A TERTIARY CARE HOSPITAL ANALYZING APTTBASED CLOT WAVEFORM PARAMETERS
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The Activated Partial Thromboxane Time (APTT) and Prothrombin Time (PT) are two coagulation times that can be measured by automated coagulation analyzers. APTT and CWA parameters are generated using the newer fully automated analyzers. The objective of this study was to analyze the morphology of clot waveforms in cases with abnormal APTT as well as their first and second derivative values. 125 patients with 20 normal controls are included in the 125 ACL TOP 300 curves for APTT. The second derivative showed early and late shoulders, biphasic peak, delayed deceleration, and biphasic peak in addition to the first derivative and second derivative. This study examined wave clot forms from 125 patients. There were 46.9 women out of 2.2 men, with a mean age of 46.1 years old. Covid (20%), liver disease (23%), polytrauma (10.4%), cardiac diseases (8.8%), sepsis/DIC (7.2%), thromboembolism (7.2%), renal disease (7.2%) were some of the clinical conditions observed. Six percent are diseases, four percent are bacterial infections, four percent is dengue, six percent is snake bite, and six percent are factor deficiencies. In terms of acceleration and deceleration peaks, liver and heart disease were significantly different, followed by sepsis, dengue, polytrauma, and sepsis/DIC. Among Covid patients, the peak of deceleration was prolonged (p<0.05). The first derivative peak was prolonged in patients with sepsis and liver disease (p 0.05). Automated coagulation analyzers all offer CWA. With a fast turnaround time, it is inexpensive. The wave pattern was tracked both quantitatively and qualitatively, using velocity, acceleration, and clot formation details. In order to identify quantitative and qualitative parameters of CWA, we performed an APTT test on automated analyzersddd