| Altered platelets have been reported in patients with diabetes mellitus and MS has been considered as a ‘prothrombotic
state’ with enhanced platelet reactivity. They have been associated with increased risk of vascular complications in these
patients. Platelet indices correlate with functional status of platelets and is an emerging risk factor of vascular
complications in diabetes and MS. The study was undertaken to know the efficacy of platelet analysis in assessing the
prognosis of diabetes mellitus and MS. Results of our study may lay a foundation for a discovery of new approaches for
prevention and treatment of cardiovascular complications in MetS and DMT2 in early stages of metabolic disorders in
patients. MetS is a proinflammatory and prothrombotic state, characterized by alteration of platelet indices. Plateletcrit was
shown to be a significant biomarker along with other parameters, including waist circumference,SBP, and serum
triglyceride levels. Platelet activation causes high risk of cardiovascular complications in MetS. T2 DM is associated with
the changes in the intra cellular signaling systems regulating platelet functionsddd |
